Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sox2  SRY (sex determining region Y)-box 2   (Synonyms: lcc, Sox-2, ysb)
Results	Reference
1*	J:119175 Donner AL, Episkopou V, Maas RL, Sox2 and Pou2f1 interact to control lens and olfactory placode development. Dev Biol. 2007 Mar 15;303(2):784-799
1	J:305862 Eze UC, Bhaduri A, Haeussler M, Nowakowski TJ, Kriegstein AR, Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia. Nat Neurosci. 2021 Apr;24(4):584-594
1	J:98458 Kiernan AE, Pelling AL, Leung KK, Tang AS, Bell DM, Tease C, Lovell-Badge R, Steel KP, Cheah KS, Sox2 is required for sensory organ development in the mammalian inner ear. Nature. 2005 Apr 21;434(7036):1031-5
1	J:160591 Liu Z, Owen T, Zhang L, Zuo J, Dynamic expression pattern of Sonic hedgehog in developing cochlear spiral ganglion neurons. Dev Dyn. 2010 Jun;239(6):1674-83
1	J:109351 Miller LA, Smith AN, Taketo MM, Lang RA, Optic cup and facial patterning defects in ocular ectoderm beta-catenin gain-of-function mice. BMC Dev Biol. 2006;6:14
1*	J:185807 Nowotschin S, Ferrer-Vaquer A, Concepcion D, Papaioannou VE, Hadjantonakis AK, Interaction of Wnt3a, Msgn1 and Tbx6 in neural versus paraxial mesoderm lineage commitment and paraxial mesoderm differentiation in the mouse embryo. Dev Biol. 2012 Jul 1;367(1):1-14
1	J:223048 Pirouz M, Pilarski S, Kessel M, A critical function of Mad2l2 in primordial germ cell development of mice. PLoS Genet. 2013 Aug;9(8):e1003712
1	J:303312 Rayon T, Stamataki D, Perez-Carrasco R, Garcia-Perez L, Barrington C, Melchionda M, Exelby K, Lazaro J, Tybulewicz VLJ, Fisher EMC, Briscoe J, Species-specific pace of development is associated with differences in protein stability. Science. 2020 Sep 18;369(6510)
1*	J:273053 Shih HP, Seymour PA, Patel NA, Xie R, Wang A, Liu PP, Yeo GW, Magnuson MA, Sander M, A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Rep. 2015 Oct 13;13(2):326-36
1	J:341534 Thawani A, Maunsell HR, Zhang H, Ankamreddy H, Groves AK, The Foxi3 transcription factor is necessary for the fate restriction of placodal lineages at the neural plate border. Development. 2023 Oct 1;150(19):dev202047
1	J:291481 Wang L, Xie J, Zhang H, Tsang LH, Tsang SL, Braune EB, Lendahl U, Sham MH, Notch signalling regulates epibranchial placode patterning and segregation. Development. 2020 Feb 17;147(4):dev183665
1	J:254919 Zhang H, Wang L, Wong EYM, Tsang SL, Xu PX, Lendahl U, Sham MH, An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis. Elife. 2017 Nov 15;6:e30126
1*	J:140027 Zou D, Erickson C, Kim EH, Jin D, Fritzsch B, Xu PX, Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear. Hum Mol Genet. 2008 Nov 1;17(21):3340-56